Periodontitis is an inflammatory gum disease that sometimes may lead to tooth loss and gum damage and even cause cardiovascular problems.
Recently, a group of Swedish scientists from Umea University researched this disorder and found a specific set of biomarkers in participants with severe forms of the disease.
Periodontitis is an inflammatory gum disease that can sometimes lead to tooth loss, gum damage, and even cardiovascular problems.
Recently, a group of Swedish scientists from Umea University researched this disorder and found a specific set of biomarkers in participants with severe forms of the disease.
Let's briefly discuss why it's important for modern dentistry and human health.
What did scientists find?
The research used data from about 1000 participants with periodontitis collected between 2007 and 2019. The study shows individuals' blood samples contain specific inflammatory protein profiles.
Also, in patients with severe forms of periodontitis, some protein levels were deficient:
- EFG – epidermal growth factor, a protein responsible for wound healing
- OLR-1 – oxidized low-density lipoprotein 1 – associated with cardiovascular diseases
What's next?
These findings are not enough to identify which traits in individuals are responsible for predispositions to severe forms of periodontitis. To complete the puzzle, scientists conduct extensive genetic research using the DNA of involved participants.
By combining these data, scientists would be able to find specific biological markers of such predispositions and shed light on the disorder's nature.
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