Sustainable production – is a modern trend that emerged as a response to global climate change and covers all manufacturing industries. Dental practices also use many chemicals, which generate waste during production stages.
This explains why, in recent years, we have observed numerous research studies examining natural substances that may become an affordable and feasible alternative to synthesized chemicals. (see more insights below the text)
And there is one more!
What did scientists find this time?
A collaborative research group from Madagascar and Italy researched the antimicrobial effect of Paederia grandidieri – the local plant from southern Madagascar – on the human oral microbiome. The reach profile of different bioactive compounds, such as iridoid glycosides, volatile oils, essential flavonoids, and many others, causes the plant's therapeutic potential.
The in-vitro experiment revealed that
- Hydro-alcoholic extract is especially effective against Listeria monocytogenes and Pseudomonas aeruginosa bacteria – important foodborne and environmental pathogens.
- Aqueous extract causes probiotic effects against Streptococcus salivarius.
Still, scientists note that in vitro research sowed only preliminary results, and for now, it's too early to state that this plant may be used for a regular medical approach. However, Paederia grandidieri extract shows promising results for dental health in laboratory conditions and medical cell cultures.
Why it's important?
Such discoveries in the future may be used in the invention of natural-based anti-biofilm medicines that replace widespread chlorhexidine, which contains some chemicals that may impact the environment.
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